Shailen K. Joshi: search on Z-Library

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1

A-887826 is a structurally novel, potent and voltage-dependent Nav1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats

Xu-Feng Zhang, Char-Chang Shieh, Mark L. Chapman, Mark A. Matulenko, Ahmed H. Hakeem, Robert N. Atkinson, Michael E. Kort, Brian E. Marron, Shailen Joshi, Prisca Honore, Connie R. Faltynek, Douglas S.

Journal:

Neuropharmacology

Year:

2010

Language:

english

File:

PDF, 395 KB

english, 2010

2

Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia

Prisca Honore, Prasant Chandran, Gricelda Hernandez, Donna M. Gauvin, Joseph P. Mikusa, Chengmin Zhong, Shailen K. Joshi, Joseph R. Ghilardi, Molly A. Sevcik, Ryan M. Fryer, Jason A. Segreti, Patricia

Journal:

Year:

2009

Language:

english

File:

PDF, 392 KB

english, 2009

3

Animal models of pain for drug discovery

Joshi, Shailen K, Honore, Prisca

Journal:

Expert Opinion on Drug Discovery

Year:

2006

Language:

english

File:

PDF, 276 KB

english, 2006

4

Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

Jun Chen, Shailen K. Joshi, Stanley DiDomenico, Richard J. Perner, Joe P. Mikusa, Donna M. Gauvin, Jason A. Segreti, Ping Han, Xu-Feng Zhang, Wende Niforatos, Bruce R. Bianchi, Scott J. Baker, Chengmi

Journal:

Year:

2011

Language:

english

File:

PDF, 384 KB

english, 2011

5

A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model

Pamela S. Puttfarcken, Ping Han, Shailen K. Joshi, Torben R. Neelands, Donna M. Gauvin, Scott J. Baker, La Geisha R. Lewis, Bruce R. Bianchi, Joseph P. Mikusa, John R. Koenig, Richard J. Perner, Micha

Journal:

Year:

2010

Language:

english

File:

PDF, 526 KB

english, 2010

6

Optimization of ADME Properties for Sulfonamides Leading to the Discovery of a T-Type Calcium Channel Blocker, ABT-639

Zhang, Qingwei, Xia, Zhiren, Joshi, Shailen, Scott, Victoria E., Jarvis, Michael F.

Journal:

ACS Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 308 KB

english, 2015

7

Estimating Efficacy and Drug ED50's Using von Frey Thresholds: Impact of Weber's Law and Log Transformation

Charles Mills, David LeBlond, Shailen Joshi, Chang Zhu, Gin Hsieh, Peer Jacobson, Michael Meyer, Michael Decker

Journal:

The Journal of Pain

Year:

2012

Language:

english

File:

PDF, 409 KB

english, 2012

8

Peripheral Opioid Modulation of Visceral Pain

G. F. GEBHART, XIN SU, SHAILEN JOSHI, N. OZAKI, J. N. SENGUPTA

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 548 KB

english, 2000

9

Corrigendum to “A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats” [Biochem. Pharmacol. 89 (4) (2014) 536–544]

Jarvis, Michael F., Scott, Victoria E., McGaraughty, Steve, Chu, Katharine L., Xu, Jun, Niforatos, Wende, Milicic, Ivan, Joshi, Shailen, Zhang, Qingwei, Xia, Zhiren

Journal:

Biochemical Pharmacology

Year:

2015

Language:

english

File:

PDF, 159 KB

english, 2015

10

5-HT, receptor agonists stimulate small intestinal transit but do not have direct visceral antinociceptive effects in the rat

Gareth A. Hicks, Nick M. Clayton, Pam J. Gaskin, Anthony J. Kirkup, Xin Su, Shailen Joshi, Ann Friedrich, Helen E. Connor, Brian Cox, David Grundy, Gerald F. Gebhart, Ptrick Pa Humphrey

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 176 KB

english, 2001

11

A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats

Jarvis, Michael F., Scott, Victoria E., McGaraughty, Steve, Chu, Katharine L., Xu, Jun, Niforatos, Wende, Milicic, Ivan, Joshi, Shailen, Zhang, Qingwei, Xia, Zhiren

Journal:

Biochemical Pharmacology

Year:

2014

Language:

english

File:

PDF, 704 KB

english, 2014

12

Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonists

Robert G. Schmidt, Erol K. Bayburt, Steven P. Latshaw, John R. Koenig, Jerome F. Daanen, Heath A. McDonald, Bruce R. Bianchi, Chengmin Zhong, Shailen Joshi, Prisca Honore, Kennan C. Marsh, Chih-Hung L

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 351 KB

english, 2011

13

Pharmacological modulation of brain activity in a preclinical model of osteoarthritis

Jaymin Upadhyay, Scott J. Baker, Rajasimhan Rajagovindan, Michelle Hart, Prasant Chandran, Bradley A. Hooker, Steven Cassar, Joseph P. Mikusa, Ann Tovcimak, Michael J. Wald, Shailen K. Joshi, Anthony

Journal:

Year:

2013

Language:

english

File:

PDF, 2.32 MB

english, 2013

14

Synthesis and biological evaluation of 5-substituted and 4,5-disubstituted-2-arylamino oxazole TRPV1 antagonists

Richard J. Perner, John R. Koenig, Stanley DiDomenico, Arthur Gomtsyan, Robert G. Schmidt, Chih-Hung Lee, Margaret C. Hsu, Heath A. McDonald, Donna M. Gauvin, Shailen Joshi, Teresa M. Turner, Regina M

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

15

TRPV1-related modulation of spinal neuronal activity and behavior in a rat model of osteoarthritic pain

Katharine L. Chu, Prasant Chandran, Shailen K. Joshi, Michael F. Jarvis, Philip R. Kym, Steve McGaraughty

Journal:

Year:

2011

Language:

english

File:

PDF, 651 KB

english, 2011

16

PARP inhibitors attenuate chemotherapy-induced painful neuropathy

Jill-Desiree Brederson, Shailen K. Joshi, Kaitlin E. Browman, Joseph Mikusa, Chengmin Zhong, Donna Gauvin, Xuesong Liu, Yan Shi, Thomas D. Penning, Alex R. Shoemaker, Vincent L. Giranda

Journal:

Journal of the Peripheral Nervous System

Year:

2012

Language:

english

File:

PDF, 531 KB

english, 2012

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